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- Proteins, from the Greek proteios, meaning first, are a class of organic
compounds which are present in and vital to every living cell.
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- In the form of skin, hair, callus, cartilage, muscles, tendons and
ligaments,
- Proteins hold together, protect, and provide structure to the body of a
multicelled organism.
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- In the form of enzymes, hormones,
antibodies, and globulins, they catalyze, regulate, and protect the body
chemistry.
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- In the form of hemoglobin, myoglobin and various lipoproteins, they
effect the transport of oxygen and other substances within an organism.
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- Proteins are generally regarded as beneficial, and are a necessary part
of the diet of all animals.
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- Humans can become seriously ill if they do not eat enough suitable
protein, the disease kwashiorkor being an extreme form of protein
deficiency.
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- Protein based antibiotics and vaccines help to fight disease
- We warm and protect our bodies with clothing and shoes that are often
protein in nature (e.g. wool, silk and leather).
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The deadly properties of protein toxins and venoms is less widely
appreciated.
- Botulinum toxin A, from Clostridium botulinum, is regarded as the most
powerful poison known.
- Based on toxicology studies, a teaspoon of this toxin would be
sufficient to kill a fifth of the world's population.
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The toxins produced by tetanus and diphtheria microorganisms are
nearly as poisonous.
- A list of highly toxic proteins or peptides would also include the
venoms of many snakes, and ricin, the toxic protein found in castor
beans.
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- Despite the variety of their physiological function and differences in
physical properties—
- silk is a flexible fiber,
- horn a tough rigid solid,
- the enzyme pepsin water soluble crystals
- Proteins are sufficiently similar in molecular structure to warrant
treating them as a single chemical family.
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- When compared with carbohydrates and lipids, the proteins are obviously
different in fundamental composition.
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- The lipids are largely hydrocarbon in nature, generally being 75 to 85%
carbon.
- Carbohydrates are roughly 50% oxygen, and like the lipids, usually have
less than 5% nitrogen (often none at all).
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- Proteins and peptides, on the other hand, are composed of 15 to 25%
nitrogen and about an equal amount of oxygen.
- The distinction between proteins and peptides is their size.
- Peptides are in a sense small proteins, having molecular weights less
than 10,000.
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15
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18
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- Other Natural Amino Acids
- The twenty alpha-amino acids listed above are the primary components of
proteins.
- Many other naturally occuring amino acids exist, and the structures of a
few of these are listed below.
- Some, such as hydroxylysine and hydroxyproline,
- These two amino acids are found only in collagen, a common structural
protein.
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